Progress in study of selective ERβ ligands / 药学学报
Acta Pharmaceutica Sinica
; (12): 658-667, 2015.
Article
em Zh
| WPRIM
| ID: wpr-257086
Biblioteca responsável:
WPRO
ABSTRACT
Estrogen receptors (ERs) are members of nuclear receptors and related to several diseases such as cancer, inflammation and osteoporosis. ERs have two forms, ERα and ERβ, which have different functions and organism distributions. Compounds selectively targeting ERβ can regulate important physiological functions and avoid the side effects caused by targeting ERα. Therefore, selective ERβ ligands have received considerable research interest in recent years. In this article, different kinds of selective ERβ ligands were summarized and their structure-activity relationships were also analyzed.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Relação Estrutura-Atividade
/
Química
/
Receptor beta de Estrogênio
/
Ligantes
Limite:
Humans
Idioma:
Zh
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2015
Tipo de documento:
Article