Identification of liposoluble constituents in Yushu tablets by UPLC-ESI-IT-TOF/MS / 药学学报
Acta Pharmaceutica Sinica
;
(12): 587-593, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-257096
ABSTRACT
In order to identify the chemical constituents of Yushu tablets comprehensively, we studied the chemical constituents of CHCl3 extract from Yushu tablets by the ultra performance liquid chromatography-electrospray ionization-ion trap-time of flight mass spectrometry (UPLC-ESI-IT-TOF/MS). It showed that there were more than 100 compounds separated, and forty-nine peaks among these were identified on the basis of high resolution mass spectrometry data and literature data reported. Determination of twelve peaks was further confirmed by standard substances. These components assigned to the different plant sources mainly included phenylpropanoids, triterpenoids, quinones and m-trihydroxybenzene compounds. By analyzing the chemical components of CHCl3 extract from compound Chinese medicine Yushu tablets comprehensively, this study provided the foundation for studying chemical components, pharmacodynamic substance and quality control of Yushu tablets.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Comprimidos
/
Medicamentos de Ervas Chinesas
/
Cromatografia Líquida de Alta Pressão
/
Cromatografia Líquida
/
Espectrometria de Massas por Ionização por Electrospray
/
Espectrometria de Massas em Tandem
Idioma:
Chinês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2015
Tipo de documento:
Artigo
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