Evaluation of Off-label Use of Oral Glucocorticoids in Outpatients / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 430-434, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-257616
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the off-label use of oral glucocorticoids in outpatients.</p><p><b>METHODS</b>The information of outpatient glucocorticoids prescriptions from January 1st to June 30th in 2012 were collected from the information system in our hospital, then the software of Excel was employed to statistically analyze the data including the amount of drugs used in different departments,as well as the age, sex, and diagnosis of the patients. The diagnoses were compared with those included in the labels approved by China Food and Drug Administration and US Food and Drug Administration and domestic and foreign guidelines.</p><p><b>RESULTS</b>It was found that 16.53% of the cases were off-label use,and dexamethasone had the highest proportion (60.50%) of off-label use. Most of the off-label use had evidence support, such as multiple myeloma and myasthenia gravis, while some cases did not, such as epilepsy and sudden deafness.</p><p><b>CONCLUSION</b>The management of off-label use should be further strengthened to promote the safe and rational use of glucocorticoids.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pacientes Ambulatoriais
/
China
/
Administração Oral
/
Epilepsia
/
Uso Off-Label
/
Glucocorticoides
Tipo de estudo:
Guia de Prática Clínica
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Chinês
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2015
Tipo de documento:
Artigo
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