Aspergillus pneumonia in renal transplant recipients / 中华医学杂志(英文版)
Chinese Medical Journal
;
(24): 791-794, 2008.
Artigo
em Inglês
| WPRIM
| ID: wpr-258590
ABSTRACT
<p><b>BACKGROUND</b>Filamentous fungal infections are associated with a high morbidity and mortality in solid organ transplants. The present study aimed to investigate the aspergillus pneumonia in renal transplant recipients, and its diagnosis as well as treatment.</p><p><b>METHODS</b>Approximately 2000 cases of renal transplants were retrospectively studied and we focused on cases hospitalized during August 1, 2005 and February 1, 2007, as the study period. The clinical database and electronic records were analyzed. Recently published literature was reviewed.</p><p><b>RESULTS</b>There was more diabetes and hypertension in the infected group than in the non-infected group (86% vs 62% and 57% vs 39%, respectively). Eighty-six percent of recipients from the infected group had delayed graft function. Seven cases with aspergillus pneumonia were identified based on either fungal culture or radiology. Of the 7 cases, 4 died in a few days after diagnosis. Liposomal amphotericin B was used as a first-line therapy.</p><p><b>CONCLUSIONS</b>Incidences of fungal infection are increasing among renal transplant recipients. Early diagnosis and treatment are critical steps in curing aspergillosis.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pneumonia
/
Aspergilose
/
Tomografia Computadorizada por Raios X
/
Estudos Retrospectivos
/
Estudos de Coortes
/
Transplante de Rim
/
Diagnóstico
/
Tratamento Farmacológico
/
Pneumopatias Fúngicas
Tipo de estudo:
Estudo diagnóstico
/
Estudo de etiologia
/
Estudo de incidência
/
Estudo observacional
/
Estudo prognóstico
/
Estudo de rastreamento
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Chinese Medical Journal
Ano de publicação:
2008
Tipo de documento:
Artigo
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