Association between Prenatal Environmental Factors and Child Autism: A Case Control Study in Tianjin, China / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
;
(12): 642-650, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-258896
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the association between autism and prenatal environmental risk factors.</p><p><b>METHODS</b>A case-control study was conducted among 193 children with autism from the special educational schools and 733 typical development controls matched by age and gender by using questionnaire in Tianjin from 2007 to 2012. Statistical analysis included quick unbiased efficient statistical tree (QUEST) and logistic regression in SPSS 20.0.</p><p><b>RESULTS</b>There were four predictors by QUEST and the logistic regression analysis, maternal air conditioner use during pregnancy (OR=0.316, 95% CI 0.215-0.463) was the single first-level node (χ²=50.994, P=0.000); newborn complications (OR=4.277, 95% CI 2.314-7.908) and paternal consumption of freshwater fish (OR=0.383, 95% CI 0.256-0.573) were second-layer predictors (χ²=45.248, P=0.000; χ²=24.212, P=0.000); and maternal depression (OR=4.822, 95% CI 3.047-7.631) was the single third-level predictor (χ²=23.835, P=0.000). The prediction accuracy of the tree was 89.2%.</p><p><b>CONCLUSION</b>The air conditioner use during pregnancy and paternal freshwater fish diet might be beneficial for the prevention of autism, while newborn complications and maternal depression might be the risk factors.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Efeitos Tardios da Exposição Pré-Natal
/
Transtorno Autístico
/
Estudos de Casos e Controles
/
Modelos Logísticos
/
China
/
Epidemiologia
/
Inquéritos e Questionários
/
Fatores de Risco
/
Exposição Paterna
/
Exposição Materna
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Adolescente
/
Criança
/
Criança, pré-escolar
/
Feminino
/
Humanos
/
Masculino
/
Gravidez
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Biomedical and Environmental Sciences
Ano de publicação:
2015
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS