Effect of 2-methacryloyloxyethyl phosphorylcholine on the protein-repellent property of dental adhesive / 中华口腔医学杂志
Chinese Journal of Stomatology
; (12): 172-175, 2016.
Article
em Zh
| WPRIM
| ID: wpr-259422
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WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the effect of 2-methacryloyloxyethyl phosphorylcholine (MPC) and nanoparticles of amorphous calcium phosphate (NACP) on the protein-repellent property of dental adhesive.</p><p><b>METHODS</b>MPC and NACP were incorporated into SBMP as the test group. Scotchbond Multi-Purpose (SBMP) was used as control group. Human dentin shear bond strengths were measured. Protein adsorption onto samples was determined by micro bicinchoninic acid (BCA) method. A dental plaque microcosm biofilm model with human saliva as inoculum was used to investigate biofilm viability.</p><p><b>RESULTS</b>The dentin bond strength of modified group was (28.7±2.2) MPa, which was not significantly different from that of the SBMP control group. The amount of protein adsorption in the modified group and the SBMP control group were (0.21±0.02) µg/cm(2) and (4.17±0.45) µg/cm(2) respectively. Lactic acid production of biofilms in modified group and SBMP control were (7.71 ± 1.01) mmol/L and (19.18 ± 2.34) mmol/L repectively.</p><p><b>CONCLUSIONS</b>MPC-NACP based dental adhesive greatly reduce the protein adsorption and bacterial adhesion, without compromising dentin shear bond strength. This novel bonding agent may have wide application.</p>
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Assunto principal:
Farmacologia
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Fosforilcolina
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Saliva
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Resistência à Tração
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Fosfatos de Cálcio
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Química
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Biofilmes
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Ácido Láctico
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Adsorção
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Cimentos de Resina
Limite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Stomatology
Ano de publicação:
2016
Tipo de documento:
Article