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Research progress on multiple myeloma immunophenotyping and minimal residual disease detected by flow cytometry / 中国实验血液学杂志
Journal of Experimental Hematology ; (6): 241-245, 2015.
Artigo em Chinês | WPRIM | ID: wpr-259607
ABSTRACT
Multiple myeloma (MM) is a haematological malignancy characterized by the accumulation of monoclonal plasma cells in the bone marrow and remained incurable. Flow cytometry has been widely used in the detection of immunophenotype and minimal residual disease, diagnosis, monitoring and prognosis of MM. Normal plasma cells and malignant plasma cells can be distinguished according to different cell surface antigen expression. The clinical significane of many immune markes has been elucidated. However, the clinical significance of some phenotype remains controversial, the detection scheme and gating strategy are not unified. This review discusses the recent research progress on detection of MM immunophenotype and minimal residual disease by flow cytovetry.
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Fenótipo / Plasmócitos / Prognóstico / Imunofenotipagem / Neoplasia Residual / Citometria de Fluxo / Mieloma Múltiplo / Antígenos de Superfície Tipo de estudo: Estudo prognóstico Limite: Humanos Idioma: Chinês Revista: Journal of Experimental Hematology Ano de publicação: 2015 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Fenótipo / Plasmócitos / Prognóstico / Imunofenotipagem / Neoplasia Residual / Citometria de Fluxo / Mieloma Múltiplo / Antígenos de Superfície Tipo de estudo: Estudo prognóstico Limite: Humanos Idioma: Chinês Revista: Journal of Experimental Hematology Ano de publicação: 2015 Tipo de documento: Artigo