Study of collagen sponge extracts on mouse splenic lymphocyte transformation in vitro / 中国医疗器械杂志
Chinese Journal of Medical Instrumentation
;
(6): 308-311, 2014.
Artigo
em Chinês
| WPRIM
| ID: wpr-259862
ABSTRACT
Immunogenicity for medical devices of animal origin is the key and difficult point during immune safety evaluation for these devices. This paper firstly investigated the effect of collagen sponge of animal origin on mouse splenic lymphocyte transformation and proliferation, and then analyzed the influence factors on the MTT method and CFSE method. The results showed that collagen sponge extract cannot significantly induce transformation and proliferation of mouse splenic lymphocyte in vitro.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Poríferos
/
Baço
/
Ativação Linfocitária
/
Células Cultivadas
/
Química
/
Colágeno
/
Biologia Celular
Limite:
Animais
Idioma:
Chinês
Revista:
Chinese Journal of Medical Instrumentation
Ano de publicação:
2014
Tipo de documento:
Artigo
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