Impact of spasmolytic on polyp and adenoma detection during colonoscopy: a meta-analysis / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
;
(12): 593-596, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-260304
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the impact of intestinal spasmolytic on colon polyps and adenoma detection rate during colonoscopy.</p><p><b>METHODS</b>Literatures related to the effect of intestinal spasmolytic on colon polyp or adenoma detection rate were retrieved from PubMed, Medline, EBSCO, High Wire Press, OVID, EMBASE, and the China National Knowledge Articles, etc. published before July 2014. Unified data were extracted by two researchers independently and organized using Jadad scale to evaluate the quality of the enrolled studies through Review manager 5.2 Meta-analysis software.</p><p><b>RESULTS</b>Six articles were enrolled with total 47,509 cases, including 16,867 cases in the scopolamine group and 30,642 cases in the placebo group. Meta analysis showed spasmolytic could increase the detective rate of polyps (OR=1.24, 95% CI1.19-1.30), adenoma (OR=1.25, 95% CI1.19-1.30) and high-risk adenoma (OR=1.22, 95% CI1.16-1.29).</p><p><b>CONCLUSION</b>Using colonoscopy spasmolytic scopolamine can increase the detection rate of colonic polyp and adenoma.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Parassimpatolíticos
/
Adenoma
/
China
/
Pólipos do Colo
/
Colonoscopia
/
Neoplasias do Colo
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo diagnóstico
/
Revisões Sistemáticas Avaliadas
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Chinês
Revista:
Chinese Journal of Gastrointestinal Surgery
Ano de publicação:
2015
Tipo de documento:
Artigo
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