Study on transdermal absorption of piperine in Erxiekang plaster / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 3294-3296, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-260668
ABSTRACT
<p><b>OBJECTIVE</b>To research the absorbed character of piperine in Erxiekang plaster, and piperine by transdermal absorption was determined.</p><p><b>METHOD</b>The percutaneous absorption of piperine in vitro at different times was conducted by Franz osmosis and diffusion apparatus as well as high-performance liquid chromatography.</p><p><b>RESULT</b>It showed that the piperine through skins of mice gradually increased within the experiment time. After 52 h, the penetration of piperine was 78.51%, and remained basically unchanged.</p><p><b>CONCLUSION</b>The method is reliable, and can be used for Erxiekang plaster of determination of transdermal absorption.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Piperidinas
/
Absorção Cutânea
/
Modelos Lineares
/
Reprodutibilidade dos Testes
/
Ratos Sprague-Dawley
/
Alcaloides
/
Benzodioxóis
/
Alcamidas Poli-Insaturadas
/
Metabolismo
Tipo de estudo:
Estudo prognóstico
Limite:
Animais
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2010
Tipo de documento:
Artigo
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