A Case of the Sign of Leser-Trelat Associated with Bladder Cancer / 대한피부과학회지

ABSTRACT

The sign of Leser-Trelat refers to the sudden appearance and rapid increase in size and number of seborrheic keratosis. It is considered to be a sign of internal malignant tumors. A 60-year-old male who had received chemotherapy for bladder cancer showed multiple rice to bean-sized dark brownish papules on the scalp and trunk. Skin lesions had suddenly appeared 4 months ago, and he had been diagnosed with transitional cell carcinoma of bladder cancer. The lesions had rapidly increased in number and size. The histopathologic finding of the skin lesions revealed seborrheic keratosis.