Study on socio-behavioral risk factors of acquired drug resistance of tuberculosis in Sichuan province / 中华流行病学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To explore the socio-behavioral risk factors on acquired drug resistance of tuberculosis (ADR-TB).</p><p><b>METHODS</b>Using pair matched case control study, 316 ADR-TB samples from 949 cases and 316 controls (pair matched for age and sex) were selected by systematical sampling method and studied through questionnaires. All the study subjects were selected from outpatients of the institute of TB control and prevention,between June 2002 and June 2005 in Sichuan province. Socio-behavioral risk factors were analyzed with conditional logistic regression and estimated with adjusted odds ratios (OR) and confidence interval (CI).</p><p><b>RESULTS</b>Data showed that the major socio-behavioral risk factors were associated with low economic status, incomplete DOTS, poor compliance and interruption during treatment with adjusted OR and CI as 5.623 (3.462-9.386), 8.875 (6.136-15.442), 6.467(3.942-10.622) and 4.906 (2.477-10.654) respectively.</p><p><b>CONCLUSION</b>ADR-TB could be controlled by taking effective measures against the socio-behavior risk factors.</p>