Studies on antibacterial constituents of Discocleidion rufescens (2) / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 1377-1380, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-263008
ABSTRACT
<p><b>OBJECTIVE</b>To screen effective constituents of Discocleidion rufescens against bacteria.</p><p><b>METHOD</b>Compounds were isolated by bioassay-guided fractionation method with various chromatographic methods and their structures were determined by spectral analysis and chemical evidence.</p><p><b>RESULT</b>Seven compounds were isolated from the Et2O and n-BuOH extracts and identified as 5,7-dihydroxy-4'-methoxy flavone (1), quercetin (2), apigenin-7-O-beta-D-glucopyranoside (3), apigenin-7-O-neohesperidoside (4), luteolin-7-O-neohesperidoside (5), gallic acid (6) and beta-daucosteol (7).</p><p><b>CONCLUSION</b>Compounds 1-6 were isolated from genus Discocleidion for the first time and exhibited certain inhibitory activity against Escherichia coli. Compound 6 also showed antibacterial activity against Staphylococus aureus.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Staphylococcus aureus
/
Extratos Vegetais
/
Química
/
Euphorbiaceae
/
Escherichia coli
/
Antibacterianos
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2009
Tipo de documento:
Artigo
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