An analysis for genetic polymorphism of twelve Y short tandem repeat loci in Chaoshan populations / 中华医学遗传学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the genetic polymorphism of twelve short tandem repeat loci of Y chromosome in Chaoshan Han populations.</p><p><b>METHODS</b>Twelve Y short tandem repeat loci, of which the template DNAs were extracted from blood samples of 121 unrelated Chaoshan Han individuals, were amplified by using the PowerPlex Y system. The PCR products were genotyped with ABI PRISM 3100 genetic analyzer.</p><p><b>RESULTS</b>From the loci DYS19, DYS437, DYS389I, DYS389II, DYS438, DYS439, DYS393, DYS391, DYS390, and DYS392, 4-7 alleles were checked out; from the loci DYS385, 35 alleles were observed. The overall observed haplotype diversity reached 0.9976. DYS391 was the locus with the lowest gene diversity (0.4445), while DYS385 had the highest gene diversity (0.9525).</p><p><b>CONCLUSION</b>The 12 Y-STR loci are highly polymorphic and suitable to forensic casework, population genetics and anthropology studies.</p>