Evaluating the Environmental Health Effect of Bamboo-Derived Volatile Organic Compounds through Analysis the Metabolic Indices of the Disorder Animal Model / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
; (12): 595-605, 2015.
Article
em En
| WPRIM
| ID: wpr-264543
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To identify the bamboo VOCs (volatile organic compounds) effect on animal physiological indices, which associated with human health.</p><p><b>METHODS</b>GC/MS was used to analyze the volatile organic compounds from Moso bamboo (Phyllostachys heterocyla cv. pubescens). The effect of VOCs on environmental health was evaluated by analyzing the metabolic indices of the type 2 diabetic mouse model.</p><p><b>RESULTS</b>Spectra of VOC generated by GC/MS were blasted against an in-house MS library confirming the identification of 33 major components that were manually validated. The relative constituent compounds as a percentage of total VOCs determined were alcohols (34.63%), followed by ether (22.02%), aldehyde (15.84%), ketone (11.47%), ester (4.98%), terpenoid (4.38%), and acids (3.83%). Further experimentation established that the metabolic incidence of the disease can be improved if treated with vanillin, leaf alcohol, β-ionone and methyl salicylate. The effects of these VOCs on type 2 diabetes were evident in the blood lipid and blood glucose levels.</p><p><b>CONCLUSION</b>Our model suggests that VOCs can potentially control the metabolic indices in type 2 diabetes mice. This experiment data also provides the scientific basis for the comprehensive utilization of ornamental bamboos and some reference for other similar study of environmental plants.</p>
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Índice:
WPRIM
Assunto principal:
Farmacologia
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Sangue
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Glicemia
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Química
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Saúde Ambiental
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Bambusa
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Diabetes Mellitus Tipo 2
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Modelos Animais de Doenças
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Compostos Orgânicos Voláteis
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Lipídeos
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Biomedical and Environmental Sciences
Ano de publicação:
2015
Tipo de documento:
Article