ATP-sensitive potassium channels: novel potential roles in Parkinson's disease / 神经科学通报·英文版
Neuroscience Bulletin
;
(6): 370-376, 2007.
Artigo
em Inglês
| WPRIM
| ID: wpr-264699
ABSTRACT
The ATP-sensitive potassium (K(ATP)) channels which extensively distribute in diverse tissues (e.g. vascular smooth muscle, cardiac cells, and pancreas) are well-established for characteristics like vasodilatation, myocardial protection against ischemia, and insulin secretion. The aim of this review is to get insight into the novel roles of K(ATP) channels in Parkinson's disease (PD), with consideration of the specificities K(ATP) channels in the central nervous system (CNS), such as the control of neuronal excitability, action potential, mitochondrial function and neurotransmitter release.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Doença de Parkinson
/
Fisiologia
/
Terapêutica
/
Canais KATP
/
Metabolismo
/
Mitocôndrias
Tipo de estudo:
Estudo diagnóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
Neuroscience Bulletin
Ano de publicação:
2007
Tipo de documento:
Artigo
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