Pathogenesis of hilar cholangiocarcinoma and infection of hepatitis virus / 中华外科杂志
Chinese Journal of Surgery
;
(12): 420-422, 2002.
Artigo
em Chinês
| WPRIM
| ID: wpr-264805
ABSTRACT
OBJECTIVE To study the correlation between hepatic hilar cholangiocarcinoma and the infection of HB (C)V. METHODS Combined with clinical data, immunohistochemistry was used to detect HBXAg antigen and HCV-C protein in 68 formalin-fixed and paraffin-embedded samples of hilar cholangiocarcinoma. RESULTS Six cases(8.8%) were positive to HBXAg antigen and 24 cases (35.0%) to HCV-C protein respectively. One case was positive to both HBXAg antigen and HCV-C protein. There were statistical differences in differentiation and invasion, lymph node metastasis, treatment between hilar cholangiocarcinomas infected HB(C)V and those non-infected. CONCLUSIONS HBXAg antigen and HCV-C protein may play an important role in the pathogenesis of hilar cholangiocarcinoma. Hilar cholangiocarcinoma infected HB(C)V may have a high malignancy and more poor prognosis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Neoplasias dos Ductos Biliares
/
Ductos Biliares Intra-Hepáticos
/
Transativadores
/
Proteínas do Core Viral
/
Hepatite C
/
Colangiocarcinoma
/
Hepatite B
Tipo de estudo:
Estudo de etiologia
/
Estudo prognóstico
Limite:
Animais
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Surgery
Ano de publicação:
2002
Tipo de documento:
Artigo
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