Microbial transformation of sinenxan A, a rich constituent in callus cultures of Taxus / 药学学报
Acta Pharmaceutica Sinica
;
(12): 555-558, 2003.
Artigo
em Chinês
| WPRIM
| ID: wpr-266638
ABSTRACT
<p><b>AIM</b>To study the microbial transformation of sinenxan A.</p><p><b>METHODS</b>Choose two strains of Fungi (Mucor spinosus AS 3.3450 and Cunninghamella echinulata AS 3.3400) and a strain of bacterium (Proteus vulgaris AS 1.1208) to transform the substrate.</p><p><b>RESULTS</b>Three products were obtained and identified as 10-deacetylsinenxan A1, 6 alpha-hydroxy-10-deacetylsinenxan A2 and 9 alpha-hydroxy-10-deacetylsinenxan A3 respectively.</p><p><b>CONCLUSION</b>Sinenxan A is facile to be transformed by microorganisms, the 10-acetyl group of which is an active group.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Plantas Medicinais
/
Proteus vulgaris
/
Biotransformação
/
Química
/
Cunninghamella
/
Taxus
/
Técnicas de Cultura
/
Diterpenos
/
Metabolismo
/
Acetatos
Idioma:
Chinês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2003
Tipo de documento:
Artigo
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