Right Common Iliac Artery Thrombosis and Aortic Artery Thrombosis Associated with Renal Infarction in Adult Minimal Change Nephrotic Syndrome / 대한신장학회잡지

ABSTRACT

The nephrotic syndrome frequently causes a hypercoagulable state, leading to thromboembolic complications in veins, but arterial thrombosis is relatively rare, and is usually associated with a poor prognosis. We report 50-year-old female patient who presented with minimal change disease complicated with aortic and right iliac arterial thrombosis. She was admitted to our hospital with severe pain in her right leg and left flank. No pulse was palpable in her right femoral artery. Aortography demonstrated a focal eccentric thrombus attached to the left wall of aorta, in which the left renal artery was occluded, and another thrombus obstructing the right common iliac artery. An emergency thrombectomy was performed. Although the patient had satisfactory reperfusion of right common iliac artery, her left renal function was not recovered. A renal biopsy revealed histologic evidence of minimal change of glomerulonephritis. After 8 weeks of steroid therapy, cytoxan was started. After 3 weeks, she developed pneumonitis and died with sepsis.