Studies on the constituents from the herb of Vernonia patula / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 235-237, 2003.
Artigo
em Chinês
| WPRIM
| ID: wpr-266779
ABSTRACT
<p><b>OBJECTIVE</b>To isolate and elucidate the chemical constituents of the whole plant of Vernonia patula, and to provide samples for biological activity screening.</p><p><b>METHOD</b>The chromatography on silica gel was used and the structures were determined by IR, NMR and MS spectra analysis and physicochemical property comparion.</p><p><b>RESULT</b>Four triterpenoids were isolated and identified as bauerenyl acetate(I), friedelin(II), epifriedelanol(III), 20(30)-taraxastene-3 beta, 21 alpha-diol(IV).</p><p><b>CONCLUSION</b>Compounds I and IV were isolated from genus Vernonia for the first time and compounds II and III were isolated from the whole plant of V. patula for the first time. The four compounds show no inhibitory effect on the growing of PC-12 cells.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ácido Oleanólico
/
Farmacologia
/
Plantas Medicinais
/
Triterpenos
/
Medicamentos de Ervas Chinesas
/
Divisão Celular
/
Química
/
Células PC12
/
Vernonia
Limite:
Animais
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2003
Tipo de documento:
Artigo
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