Epstein-Barr Virus Associated Hemophagocytic Syndrome after Scrub Typhus Infection / 감염과화학요법
Infection and Chemotherapy
;
: 330-333, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-26684
ABSTRACT
There have been a small number of cases of scrub typhus-associated hemophagocytic syndrome (HPS), most of which were treated successfully using adequate antibiotics. Here, we report a case of Epstein-Barr virus (EBV)-associated HPS after scrub typhus infection that was not improved using antirickettsial treatment. A 73-year-old male who had been diagnosed with scrub typhus according to an eschar and a positive serology was transferred to our institution because of a persistent fever despite 7-day doxycycline therapy. Physical and laboratory data showed hepatosplenomegaly, bicytopenia, hyperferritinemia, and hypofibrinogenemia. A bone marrow examination (BM) revealed hypercellular marrow with hemophagocytosis and histiocyte infiltration. EBV was detected in BM aspirates using polymerase chain reaction. After a diagnosis of HPS was made, the patient was treated successfully using high-dose steroids.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Esteroides
/
Medula Óssea
/
Exame de Medula Óssea
/
Tifo por Ácaros
/
Reação em Cadeia da Polimerase
/
Doxiciclina
/
Herpesvirus Humano 4
/
Infecções por Vírus Epstein-Barr
/
Diagnóstico
/
Linfo-Histiocitose Hemofagocítica
Tipo de estudo:
Estudo diagnóstico
Limite:
Idoso
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Infection and Chemotherapy
Ano de publicação:
2016
Tipo de documento:
Artigo
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