Identification of hydrolysates and alcoholysates of aconitum alkaloids / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1564-1569, 2012.
Article
em Zh
| WPRIM
| ID: wpr-266976
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To identify products decomposed in high temperature water and alcohol from diester alkaloids such as aconitum alkaloid, in order to study their transformation regularity.</p><p><b>METHOD</b>Structures of multiple converted products were determined by analyzing on multistage mass spectrometry of known compounds and literature searching.</p><p><b>RESULT</b>Benzaconine and pyraconitine were the major hydrolysates, while pyraconitine and ethoxy-aconitine were the major alcoholysates from diester alkaloids.</p><p><b>CONCLUSION</b>Pyraconitine alkaloids, as pyrolytic products, are not related to the type of solvent. 8-ethoxy-aconitine alkaloids, as alcoholysates, are related to the type of solvent. This study identifies multiple converted products from alkaloids and summarizes mass spectrometry fragmentation regularity by LC-MS, laying a firm foundation for studies on the transformation of toxic diester alkaloids contained in aconitum and providing a basis for studies on the transformation of alkaloids contained in aconitum during boiling.</p>
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Índice:
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Assunto principal:
Espectrometria de Massas
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Química
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Aconitum
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Etanol
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Alcaloides
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Hidrólise
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2012
Tipo de documento:
Article