Flocculation process of aqueous extracts of zhisou dingchuan oral solution with quaternary ammonium salt of chitosan / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 1212-1218, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-267046
ABSTRACT
<p><b>OBJECTIVE</b>To study the effect of quaternary ammonium salt of chitosan (HACC) in purifying aqueous extracts of Zhisou Dingchuan oral solution.</p><p><b>METHOD</b>Modified quaternary ammonium salt of chitosan was used to flocculate aqueous extracts of Zhisou dingchuan oral solution, with turbidity degree and the retention rate of ephedrine and glycyrrhizin as indicators, to detect the influences of flocculant dosage, suspension temperature, mixing speed and time on flocculation effect. The optimum process conditions were found through orthogonal experimental design.</p><p><b>RESULT</b>The optimum process conditions the flocculation temperature 30 degrees C, HACC's dosage 0.4 g x L(-1), the fast mixing speed 500 r x min(-1) and its time 1 min, the slow mixing speed 50 r x min(-1) and it time 2.4 10 min. Under the conditions, the retention rate of ephedrine was 97.6%, the turbidity degree was 1.1 NTU and 2.8 NTU after 30 days.</p><p><b>CONCLUSION</b>HACC can be used to purify aqueous extracts of Zhisou Dingchuan oral solution.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Soluções
/
Medicamentos de Ervas Chinesas
/
Química
/
Quitosana
/
Floculação
/
Compostos de Amônio Quaternário
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2012
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS