Effect of benzene on sperm DNA / 中华男科学杂志
National Journal of Andrology
;
(12): 53-55, 2005.
Artigo
em Chinês
| WPRIM
| ID: wpr-267757
ABSTRACT
<p><b>OBJECTIVE</b>To assess the effect of benzene on sperm DNA.</p><p><b>METHODS</b>Twenty-seven workers exposed to benzene for over two years were included in the experiment group and 35 unexposed ones were chosen as controls. Damage by benzene on sperm DNA was detected by modified single cell gel electrophoresis (SCGE).</p><p><b>RESULTS</b>The benzene concentration in the air of the workplace of the exposed workers was (86.49 +/- 2.83) mg/m3, twice that of the national maximum allowance (40 mg/cm3). Urinary, trans-muconic acid in the exposed group was (1.40 +/- 0.62) mg/L (n = 27), significantly higher than that of the controls [(0.82) +/- 0.16) mg/L, n = 35]. After SCGE, the percentage of head DNA in the exposed group [(70.18% +/- 7.36%, n = 13 ] was significantly lower than that of the controls (90.62% +/- 2.94%, n = 16), P < 0.001.</p><p><b>CONCLUSION</b>Higher concentration of benzene could cause damage to the sperm DNA of the workers exposed to it.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Espermatozoides
/
Benzeno
/
Dano ao DNA
/
Inquéritos e Questionários
/
Exposição Ocupacional
/
Ensaio Cometa
/
Poluentes Ocupacionais do Ar
/
Toxicidade
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
National Journal of Andrology
Ano de publicação:
2005
Tipo de documento:
Artigo
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