Preventive administration of antibiotics to patients with benign prostatic hyperplasia before urodynamic examination / 中华男科学杂志
National Journal of Andrology
; (12): 996-998, 2013.
Article
em Zh
| WPRIM
| ID: wpr-268016
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To discuss the effect and safety of preventive administration of antibiotics to patients with benign prostatic hyperplasia (BPH) before urodynamic examination.</p><p><b>METHODS</b>A total of 256 BPH patients to undergo urodynamic examination were randomly divided into a control group (n = 118) and a trial group (n = 138). The former received no pre-treatment while the latter were given cefoxitin sodium iv at 1.0 g 30 minutes before complete urodynamic examination. Then we compared the incidence rates of urinary tract infection between the two groups.</p><p><b>RESULTS</b>Statistically significant differences were found in the incidence rate of urinary tract infection between the control and trial groups (20.3% [24/118] vs 7.3% [10/138], P < 0.01), as well as in those with diabetes mellitus (6.7% [3/45] vs 23.5% [8/34], P < 0.05), those with residual urine > 50 ml (5.4% [3/56] vs 18.5% [10/54], P < 0.05), and those with both diabetes mellitus and residual urine (9.5% [2/21] vs 44.4% [8/18], P < 0.05). Only 3 patients (2.2%) in the trial group had mild adverse drug reactions.</p><p><b>CONCLUSION</b>For BPH patients, particularly those with diabetes mellitus and residual urine, preventive administration of antibiotics before urodynamic examination is safe and can effectively protect the patients against urinary tract infection.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Hiperplasia Prostática
/
Infecções Urinárias
/
Urodinâmica
/
Cefoxitina
/
Antibioticoprofilaxia
/
Diagnóstico
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
/
Male
Idioma:
Zh
Revista:
National Journal of Andrology
Ano de publicação:
2013
Tipo de documento:
Article