Advances in the study of A2B adenosine receptor antagonists / 药学学报
Acta Pharmaceutica Sinica
;
(12): 241-246, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-268138
ABSTRACT
A2B adenosine receptor is involved in the control of mast cell degranulation, interleukin-8 synthesis and cell growth. A2B adenosine receptor antagonists may serve as novel drugs for asthma, Alzheimer' s disease, cystic fibrosis and type-II diabetes. Therefore, seeking for the highly selective A2B adenosine receptor antagonists has been one of great interest. The molecular basis, structure-activity relationship of selective A2B adenosine receptor antagonists and their interactions with A2B adenosine receptor were reviewed.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Artéria Pulmonar
/
Asma
/
Relação Estrutura-Atividade
/
Xantinas
/
Adenosina
/
Antiasmáticos
/
Adenosina-5'-(N-etilcarboxamida)
/
Usos Terapêuticos
/
Tratamento Farmacológico
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2008
Tipo de documento:
Artigo
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