Biology of thioredoxin and its association with Alzheimer's disease and Parkinson's disease / 药学学报
Acta Pharmaceutica Sinica
;
(12): 1-8, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-268181
ABSTRACT
Thioredoxin (Trx) is a crucial protein for antioxidative defense, as well as a redox regulator of the intra- and extracellular signaling pathways and transcription factors. In this review, we focus on mammalian Trx and its association with Alzheimer's disease (AD) and Parkinson's disease (PD). Based on the evidence of neuroprotective effects of Trx, up-regulation of Trx may be a good strategy for prevention and treatment of AD and PD.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Oxirredução
/
Doença de Parkinson
/
Fisiologia
/
Tiorredoxinas
/
Apoptose
/
Fármacos Neuroprotetores
/
Doença de Alzheimer
/
Metabolismo
/
Antioxidantes
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2008
Tipo de documento:
Artigo
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