Structure modification on sesquiterpene lactones from Elephantopus scaber / 药学学报
Acta Pharmaceutica Sinica
;
(12): 1159-1161, 2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-268212
ABSTRACT
In order to look for lower toxic and strongly active compounds, the structure of sesquiterpene lactones from Elephantopus scaber was modified. Deoxyelephantopin and scabertopin were isolated from the whole plant of Elephantopus scaber and hydrogenated and epoxidated. Five sesquiterpenoide derivatives were prepared and their structures were identified by IR, NMR and MS spectra analysis. Four sesquiterpenoides are new compounds. Part of the compounds show definite antitumor activity.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Plantas Medicinais
/
Sesquiterpenos
/
Terpenos
/
Células HeLa
/
Estrutura Molecular
/
Química
/
Asteraceae
/
Hidrogenação
/
Lactonas
Limite:
Humanos
Idioma:
Chinês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2007
Tipo de documento:
Artigo
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