Clinicopathologic analysis of myocardial infarction with or without left ventricular aneurysm formation in the elderly patients / 中华心血管病杂志

ABSTRACT

<p><b>OBJECTIVE</b>To analyze the clinic-pathologic features of elderly myocardial infarction patients (> 60 years) with and without left ventricular aneurysm formation.</p><p><b>METHODS</b>Between January 1980 and October 2009, 107 myocardial infarction patients were divided into aneurysm group (n = 31) and non-aneurysm group (n = 76) according to autopsy results and the clinic-pathologic features of the two groups were compared.</p><p><b>RESULTS</b>Previous angina pectoris history was significantly less in aneurysm group than in non-aneurysm group [45.2% (14/31) vs. 92.1% (70/76), P = 0.047]. Incidence of hypertension was significantly higher in aneurysm group than in non-aneurysm group [77.4% (24/31) vs. 36.8% (28/76), P = 0.033]. The percentage of single-vessel disease [54.8% (17/31) vs. 23.7% (18/76), P = 0.033] and the LAD disease [96.8% (30/31) vs. 51.3% (39/76), P = 0.048] were both significantly higher in aneurysm group than in non-aneurysm group. Heart failure and ventricular arrhythmias were more likely the cause of death in patients with aneurysm than patients without aneurysm [56.3% (18/31) vs. 19.7% (15/76), P = 0.007]. Aneurysm mostly located in left ventricular anterior wall and apex.</p><p><b>CONCLUSIONS</b>Our results suggest that patients with left ventricular aneurysm formation are more likely to have hypertension, single-vessel disease and LAD disease, heart failure and ventricular arrhythmias but less previous angina pectoris than patients without left ventricular aneurysm formation. The common locations of ventricular aneurysm formation were left ventricular anterior wall and apex.</p>