Blood lactic acid level and APACHE II score on prognosis of critically ill elderly patients / 中华流行病学杂志

ABSTRACT

Objective To analyze the relevance between blood lactic acid level and acutephysiology and chronic health evaluation Ⅱ (APACHE Ⅱ ) score in order to provide guideline for clinical treatment.Methods Retrospective analyses on 537 critically ill elderly patients who were hospitalized in the ICU with their blood lactic acid level tested and APACHE Ⅱ scores calculated.Results The overall death rate was 35.75％ (192/537) with the APACHE Ⅱ score as (22.6 ± 12.8),and blood lactic acid level as (6.84 ± 2.01 ) mmol/L.The blood lactic acid level among deaths was obviously higher than in the control group,with significant differences (P＜0.05).The level of blood lactic acid was positively related to APACHE Ⅱ score (r=0.572,P＜0.05) while the death rate was both positively related to APACHE Ⅱ score (r=0.475,P＜0.05) and the level of blood lactic acid (r=0.506,P＜0.05).Conclusion There seemed a positive correlation between blood lactic acid level and the APACHE Ⅱscore.Both of them showed good relevancc with thc prognosis of the disease.