Significance of exhaled nitric oxide measurement in remitting childhood asthma with concurrent remitting rhinitis / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
; (12): 161-164, 2014.
Article
em Zh
| WPRIM
| ID: wpr-269517
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the value of exhaled nitric oxide in the severity evaluation of asthmatic children with remitting rhinitis.</p><p><b>METHODS</b>A total of 214 asthmatic children were randomly allocated to a untreated control and a conventional treatment group. Patients in each of the two subclasses were classified as asthma with concurrent rhinitis and asthma without concurrent rhinitis. Values of the 20% fall in forced expiratory volume in 1 second (PC20FEV1) and fractional exhaled nitric oxide (FeNO) were measured.</p><p><b>RESULTS</b>The PC20FEV1 level was significantly higher in untreated asthma patients without rhinitis than in those with concurrent rhinitis (P<0.05), while FeNO was not significantly different between these two groups (P>0.05). There were no significant differences in both FeNO and PC20FEV1 between treated asthma patients with and without concurrent rhinitis (P>0.05). PC20FEV1 was significantly increased (P<0.05) but FeNO was significantly decreased (P<0.05) in asthma patients with concurrent rhinitis after conventional treatment. In asthmatic children without concurrent rhinitis, treatment significantly decreased the level of FeNO (P<0.05) but had not effect on PC20FEV1 (P>0.05).</p><p><b>CONCLUSIONS</b>Exhaled nitric oxide measurement may be useful in the severity evaluation of asthmatic children with remitting rhinitis.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Asma
/
Índice de Gravidade de Doença
/
Testes Respiratórios
/
Rinite Alérgica Perene
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Diagnóstico
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Rinite Alérgica
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Óxido Nítrico
Tipo de estudo:
Diagnostic_studies
Limite:
Adolescent
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Child
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Child, preschool
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Chinese Journal of Contemporary Pediatrics
Ano de publicação:
2014
Tipo de documento:
Article