Study of 17 immune cytokines in the peripheral blood of premature infants with chronic lung disease / 南方医科大学学报
Journal of Southern Medical University
;
(12): 331-333, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-269558
ABSTRACT
<p><b>OBJECTIVE</b>To explore the immunomechanism of chronic lung disease (CLD) in premature infants by investigating the changes of 17 cytokines.</p><p><b>METHODS</b>Twenty-six preterm neonates who had been in the NICU for over 28 days were divided into CLD group (n=14) and control group consisting of 12 preterm neonates. Seventeen cytokines, namely interleukin 1b (IL-1b), IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12, IL-13, IL-17, granulocyte-macrophage colony-stimulating factor, interferon-gamma, tumour necrosis factor alpha, granulocyte colony-stimulating factor, monocyte chemoattractant protein 1, and macrophage inflammatory protein-1b were detected in a single sample of peripheral blood by multi-plex technology (Bio-plex).</p><p><b>RESULTS</b>There were no significant differences in the level of the 17 cytokines between the two groups (P>0.05).</p><p><b>CONCLUSION</b>The cytokines examined may not be involved in the later period pathogenesis of CLD.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Sangue
/
Recém-Nascido Prematuro
/
Doença Crônica
/
Citocinas
/
Interleucinas
/
Interferon gama
/
Fator de Necrose Tumoral alfa
/
Alergia e Imunologia
/
Pneumopatias
Limite:
Feminino
/
Humanos
/
Masculino
/
Recém-Nascido
Idioma:
Chinês
Revista:
Journal of Southern Medical University
Ano de publicação:
2010
Tipo de documento:
Artigo
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