Lymphangiogenesis, lymphatic endothelial cells and lymphatic metastasis in head and neck cancer--a review of mechanisms / 国际口腔科学杂志·英文版
International Journal of Oral Science
;
(4): 5-14, 2010.
Artigo
em Inglês
| WPRIM
| ID: wpr-269727
ABSTRACT
Lymphatic metastasis is a continuous and complicated process. The detailed mechanisms of lymphatic metastasis are still not very clear, despite considerable research efforts in recent years. Previously, it was commonly accepted that there were no lymphatic vessels in the primary tumor. However, recent studies have demonstrated that lymphatic vessels are detectable in certain types of cancer, and more and more evidence has shown that cancer cells invade into local lymph nodes mainly via peritumoral lymphatic vessels. Moreover, activated endothelial cells may also be important, having an influence on lymphatic metastasis of cancer cells. This article, based on recent research findings, provides an in-depth discussion of the relationship between lymphangiogenesis, tumor-derived lymphatic endothelial cells and lymphatic metastasis in head and neck cancer.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Fisiologia
/
Endotélio Linfático
/
Carcinoma de Células Escamosas
/
Células Endoteliais
/
Linfangiogênese
/
Neoplasias de Cabeça e Pescoço
/
Metástase Linfática
/
Invasividade Neoplásica
Tipo de estudo:
Pesquisa qualitativa
Limite:
Humanos
Idioma:
Inglês
Revista:
International Journal of Oral Science
Ano de publicação:
2010
Tipo de documento:
Artigo
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