Progress of study on brain protective effect and mechanism of Polygonum multiflorum / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
;
(12): 955-959, 2005.
Artigo
em Chinês
| WPRIM
| ID: wpr-269857
ABSTRACT
This paper reviews the brain protective effect and mechanism of Polygonum multiflorum (PM), its extracts and active component, tetrahydroxystilbene-glucoside (2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside) published in recent decade. They have major effects as calcium channel antagonists, antioxidant, cholinomimetic drugs and cholinesterase inhibitors, as well as actions in regulating cell apoptosis and prolonging the ageing. The brain protective mechanism of PM is multi-target, multi-link and multi-way. Therefore, PM has great applicative value in prevention and treatment of senile neuropathies, such as Alzheimer's disease, Parkinson's disease and vascular dementia, etc.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Estilbenos
/
Medicamentos de Ervas Chinesas
/
Extratos Vegetais
/
Bloqueadores dos Canais de Cálcio
/
Química
/
Fármacos Neuroprotetores
/
Polygonum
/
Tratamento Farmacológico
/
Glucosídeos
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Integrated Traditional and Western Medicine
Ano de publicação:
2005
Tipo de documento:
Artigo
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