The advance of model of action in low-dose chronic benzene exposure induced hematotoxicity / 中华预防医学杂志
Chinese Journal of Preventive Medicine
;
(12): 840-843, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-269982
ABSTRACT
Benzene is classified as Group 1 carcinogen by IARC. It has been found that benzene induces hematotoxicity even in low dose exposure. The identification of key events during benzene induced hematotoxicty leads to adjustment of occupational exposure limits of benzene. In this review, we focus on the exposure, metabolism, target organs, key epigenetic changes, toxicty effects and end points of low-dose chronic benzene exposure induced hematotoxicity and finally discuss the perspectives on the future study of this area.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Benzeno
/
Carcinógenos
/
Exposição Ocupacional
/
Epigênese Genética
/
Toxicidade
Limite:
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Preventive Medicine
Ano de publicação:
2015
Tipo de documento:
Artigo
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