A Fatal Spontaneous Gas Gangrene due to Clostridium perfringens during Neutropenia of Allogeneic Stem Cell Transplantation: Case Report and Literature Review / 감염과화학요법
Infection and Chemotherapy
;
: 199-203, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-27051
ABSTRACT
Most cases of gas gangrene caused by Clostridium species begin with trauma-related injuries but in rare cases, spontaneous gas gangrene (SGG) can occur when patients have conditions such as advanced malignancy, diabetes, or immunosuppression. Clostridium perfringens, a rare cause of SGG, exists as normal flora of skin and intestines of human. Adequate antibiotics with surgical debridement of infected tissue is the only curative therapeutic management. Mortality rate among adults is reported range of 67-100% and majority of deaths are occurred within 24 hours of onset. We experienced a case of SGG on the trunk, buttock and thigh in a neutropenic patient with acute lymphoblastic leukemia. His clinical course was rapid and fatal during pre-engraftment neutropenic period of allogeneic stem cell transplantation.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pele
/
Coxa da Perna
/
Nádegas
/
Mortalidade
/
Terapia de Imunossupressão
/
Clostridium
/
Clostridium perfringens
/
Desbridamento
/
Transplante de Células-Tronco
/
Leucemia-Linfoma Linfoblástico de Células Precursoras
Tipo de estudo:
Estudo prognóstico
Limite:
Adulto
/
Humanos
Idioma:
Inglês
Revista:
Infection and Chemotherapy
Ano de publicação:
2014
Tipo de documento:
Artigo
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