Influence of soy isoflavone on lindane cumulant in sprague-dawley rats / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
;
(12): 637-640, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-270557
ABSTRACT
Female Sprague-Dawley rats weighing 60-80 g were given different dosages of soy isoflavones and/or lindane for four weeks. Soy isoflavones was added in feed and lindane was given by oral gavage. We found that soy isoflavones could reduce the level of lindane in rat's serum and brain, but might cause the uterus hyperplasia. Lindane could inhibit the effect of soy isoflavones on uterus and significantly decrease the level of estradiol and testosterone in serum. This study indicated that soy isoflavones could reduce the level of lindane in rat's body. Lindane could reduce the level of hormones and decreased the effect of soy isoflavones on rat's uterus.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Glycine max
/
Testosterona
/
Útero
/
Hexaclorocicloexano
/
Sangue
/
Encéfalo
/
Química
/
Ratos Sprague-Dawley
/
Estradiol
Limite:
Animais
Idioma:
Inglês
Revista:
Biomedical and Environmental Sciences
Ano de publicação:
2014
Tipo de documento:
Artigo
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