Your browser doesn't support javascript.
loading
Lepidium meyenii (Maca) reduces spermatogenic damage induced by a single dose of malathion in mice / 亚洲男科学杂志(英文版)
Asian Journal of Andrology ; (6): 71-76, 2005.
Artigo em Inglês | WPRIM | ID: wpr-270870
ABSTRACT
<p><b>AIM</b>To observe the effect of the aqueous extract of hypocotyls of the plant Lepidium meyenii (Maca) on spermatogenic damage induced by the organophosphate insecticide malathion in mice.</p><p><b>METHODS</b>Mice were treated with 80 mg/kg of malathion in the presence or absence of an aqueous extract of Maca, which was orally administered 7, 14 or 21 days after injection of the malathion. Stages of the seminiferous epithelium were assessed by transillumination on days 0, 7, 14 and 21.</p><p><b>RESULTS</b>The administration of Maca increased significantly the length of stage VIII on days 7, 14 and 21 of treatment compared with the controls. An increase in the length of stage IX occurred on day 14 of treatment. Malathion affected spermatogenesis by reducing the lengths of stage IX on day 7, stages VII and IX-XI on day 14 and a recovery of stages IX-XII on day 21. The magnitude of alteration in the length of stage IX produced by malathion was significantly reduced by Maca on days 7 and 14. The length of stage VIII was increased when Maca was administered to mice treated with malathion. Assessment of the relative length of stages of the seminiferous epithelium showed that Maca treatment resulted in rapid recovery of the effect of malathion.</p><p><b>CONCLUSION</b>Maca enhances spermatogenesis following spermatogenic damage caused by the organophosphorous pesticide.</p>
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Espermatogênese / Fatores de Tempo / Esquema de Medicação / Extratos Vegetais / Resultado do Tratamento / Hipocótilo / Lepidium / Usos Terapêuticos / Malation / Fitoterapia Limite: Animais Idioma: Inglês Revista: Asian Journal of Andrology Ano de publicação: 2005 Tipo de documento: Artigo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Espermatogênese / Fatores de Tempo / Esquema de Medicação / Extratos Vegetais / Resultado do Tratamento / Hipocótilo / Lepidium / Usos Terapêuticos / Malation / Fitoterapia Limite: Animais Idioma: Inglês Revista: Asian Journal of Andrology Ano de publicação: 2005 Tipo de documento: Artigo