Endotoxins in the prostatic secretions of chronic prostatitis patients / 亚洲男科学杂志(英文版)
Asian Journal of Andrology
;
(6): 45-47, 2005.
Artigo
em Inglês
| WPRIM
| ID: wpr-270874
ABSTRACT
<p><b>AIM</b>To evaluate the clinical significance of the quantitative determinations of endotoxins in the expressed prostatic secretions (EPS) of chronic prostatitis (CP) patients.</p><p><b>METHODS</b>The EPS of 45 patients with CP and 15 normal volunteers were obtained for microscopic examination, bacterial culture and endotoxin determination. The level of endotoxins was determined by the Limulus-amebocyte-lysate test with chromogenic substrate.</p><p><b>RESULTS</b>Patients with CP had higher mean levels of endotoxins in EPS than normal volunteers [52.06 +/- 32.83 EU/L vs. 4.77 +/- 4.14 EU/L (P <0.05)]. The levels of endotoxins in CP type II, type IIIa and type IIIb were 68.62 +/- 34.78 EU/L, 45.30 +/- 23.33 EU/L and 15.83 +/- 5.31 EU/L, respectively [type II vs. type IIIa (P >0.05), type IIIb vs. normal controls (P <0.05), type II/type IIIa vs. normal controls P >0.05)].</p><p><b>CONCLUSION</b>CP patients have elevated levels of endotoxins in the EPS, which suggests that inflammation is a feature of this disease. EPS endotoxin determination is not only helpful in diagnostic confirmation, but also in evaluating the response to treatment in CP patients.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Próstata
/
Prostatite
/
Infecções Bacterianas
/
Estudos de Casos e Controles
/
Doença Crônica
/
Sensibilidade e Especificidade
/
Secreções Corporais
/
Diagnóstico
/
Endotoxinas
/
Metabolismo
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Asian Journal of Andrology
Ano de publicação:
2005
Tipo de documento:
Artigo
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