Women with poor response to ovarian stimulation have increased follicular bone morphogenetic protein-15 levels / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 439-442, 2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-271506
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the levels of bone morphogenetic protein-15 (BMP-15) in human follicular fluid (FF) and its association with response to ovarian stimulation.</p><p><b>METHODS</b>Western blotting was performed to determine the levels of BMP-15 in FF obtained from follicle aspirates in 70 patients undergoing IVF treatment. According to the response to ovarian stimulation the patients were divided into poor responder group and normal responder group.</p><p><b>RESULT</b>BMP-15 levels in FF of poor responders were significantly higher than those in normal responders (1.01 +/- 0.34 vs 0.77 +/- 0.24, P<0.01).</p><p><b>CONCLUSION</b>Increased levels of BMP-15 in FF may be associated with poor response to ovarian stimulation.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ovário
/
Indução da Ovulação
/
Líquido Folicular
/
Western Blotting
/
Hormônio Liberador de Gonadotropina
/
Peptídeos e Proteínas de Sinalização Intercelular
/
Proteína Morfogenética Óssea 15
/
Fator 9 de Diferenciação de Crescimento
/
Hormônio Foliculoestimulante
/
Infertilidade Feminina
Limite:
Adulto
/
Feminino
/
Humanos
Idioma:
Chinês
Revista:
Journal of Zhejiang University. Medical sciences
Ano de publicação:
2007
Tipo de documento:
Artigo
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