Effect of gufuhuotang on hemorheology and lipid metabolism of hormonal necrosis of femoral head / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 769-771, 2002.
Artigo
em Chinês
| WPRIM
| ID: wpr-271818
ABSTRACT
<p><b>OBJECTIVE</b>To probe the of Gufuhuotang effect on hemorheology and lipid metabolism of hormonal necrosis of femoral head.</p><p><b>METHOD</b>32 male rabbits of New Zealand were divided at random into pathological pattern group, normal control group, low-dosage of Gufuhuotang group and high-dosage group; models of osteocyte necrosis of head of femur were made with intragluteal injection of hydroprednisone acetate; the rabbits were observed weekly and killed 6 weeks later and HE pathological section was made to observe hemorheology index and blood-liquid content, and then analysis and comparison were made.</p><p><b>RESULT</b>Gufuhuotang could obviously decrease total blood low-shear viscosity, plasma viscosity, hemacocrit, serum cholesterol and triglyceride contents; under light microscope empty bone lacunas of femoral head were less, fat cells of medullary cavity were less and relatively small, and bone trabecula was sparse with no break.</p><p><b>CONCLUSION</b>Gufuhuotang has a distinct preventive and curative effect on rabbits' hormonal necrosis of femoral head.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Plantas Medicinais
/
Sangue
/
Prednisona
/
Medicamentos de Ervas Chinesas
/
Distribuição Aleatória
/
Química
/
Hemorreologia
/
Usos Terapêuticos
/
Combinação de Medicamentos
/
Necrose da Cabeça do Fêmur
Limite:
Animais
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2002
Tipo de documento:
Artigo
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