Relationship between blood lactate level and disease severity in critically ill children / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 114-116, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-272379
ABSTRACT
<p><b>OBJECTIVE</b>To study the relationship between blood lactate level and disease severity in critically ill children.</p><p><b>METHODS</b>The clinical data of 232 children who were critically ill between September and December, 2010 were retrospectively studied. According to blood lactate levels within 24 hrs of admission, the 232 patients were classified into three groups normal (n=146), high lacticemia (n=72) and lactic acidosis (n=14). The circulation functions, pediatric critical illness scores and prognosis were compared among the three groups.</p><p><b>RESULTS</b>The degree of sepsis among the three groups was different (χ2 = 13.592, P<0.01). The occurrence of septic shock in the lactic acidosis group (42.9%) was significant compared with that in the normal (7.5%) and the high lacticemia groups (11.1%). The pediatric critical illness scores were different among the three groups (χ2 = 12.854, P<0.05). The blood lactate level was significantly negatively correlated with the pediatric critical illness scores (r=-0.405, P=0.002). The prognosis among the three groups was also varied (χ2 = 25.599, P<0.01). The curative rate (7.1% vs 23.3%; P<0.05) and the improvement rate (28.6% vs 58.2%; P<0.05) in the lactic acidosis group were significantly lower than in the normal group, and the mortality (28.6%) was significantly higher than in the normal (5.5%) and the high lacticemia groups (6.9%).</p><p><b>CONCLUSIONS</b>A higher blood lactic acid level is associated with a more severe illness state and a worse prognosis.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prognóstico
/
Sangue
/
Índice de Gravidade de Doença
/
Estudos Retrospectivos
/
Estado Terminal
/
Ácido Láctico
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Adolescente
/
Criança
/
Criança, pré-escolar
/
Feminino
/
Humanos
/
Lactente
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Contemporary Pediatrics
Ano de publicação:
2012
Tipo de documento:
Artigo
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