Pathogenesis and Prevention of Transfusion-Associated Graft-versus-Host Disease / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1774-1779, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-272523
ABSTRACT
Transfusion-associated graft-versus-host disease (TA-GVHD) is a rare complication of blood transfusion. The disease is fulminant and fatal in most patients. TA-GVHD is caused by transfused alloreactive donor T lymphocytes that attack host tissue, including skin, liver, gastrointestinal tract and bone marrow. Most patients are immunocompromised, but immunocompetent patients can also be involved. Irradiation of blood components is generally recommended to prevent the onset of TA-GVHD for susceptible recipients. This review focus on pathogenesis and prevention of TA-GVHD.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Doadores de Tecidos
/
Transfusão de Sangue
/
Medula Óssea
/
Linfócitos T
/
Trato Gastrointestinal
/
Doença Enxerto-Hospedeiro
/
Fígado
Tipo de estudo:
Estudo de etiologia
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Experimental Hematology
Ano de publicação:
2015
Tipo de documento:
Artigo
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