Comparison of 4 types of coronary heart disease model of Qi-deficiency and blood-stasis syndrome in rats / 中国中药杂志

ABSTRACT

This paper was aimed to establish a method for coronary heart disease in rats with Qi-deficiency and blood stasis of the stable by comparing different model establishment methods (L group ligation of coronary artery, EL group exercise fatigue combine ligation of coronary artery, DL group diet combine ligation of coronary artery, DEL group diet, exercise fatigue combine ligation of coronary artery). After 6 weeks postoperatively, both the method of L (ligation of coronary artery) and DL, EL, DEL (multi-originated information complex) could be successfully established by coronary heart disease model of Qi-deficiency and blood-stasis syndrome type in rats. Model set up by using the compound factors (DL, EL, DEL), and through simple ligation of coronary artery to build model (L) to compare the clinical etiology and linked, DL, EL and DEL were more closely with relevant theoretical system of traditional Chinese medicine (TCM) and have a certain advantage in complete reflect the characteristics of TCM syndrome. Among three kinds of compound factors model, EL model compared with other two models DL and DEL was more consistent with clinical practical reasons and characteristics of the disease. Through EL the CHD deficiency of blood stasis rat model of combined disease could be controlled and good repeated.