Determination of doping in human urine by gas chromatography-high resolution mass spectrometry / 药学学报
Acta Pharmaceutica Sinica
;
(12): 1667-1670, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-274606
ABSTRACT
A method was evaluated for determination of twenty-one doping (including nandrolone, boldenone and methandienone) in human urine by gas chromatography-high resolution mass spectrometry. Samples were prepared by liquid-liquid extraction, concentrated, TMS derivatization and limit of detection at ng x mL(-1) by MID/GC/HRMS. According to the code of the World Anti-Doping Agency (WADA), precision and recoveries of the procedure were evaluated by replicate analysis (n = 6), the recoveries in the range of 66%-103%, with the RSD below 10.0%. The precision within the day of the method with three different concentrations was also determined RSD were less than 9.5%, 10.0% and 9.7%.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Testosterona
/
Urina
/
Detecção do Abuso de Substâncias
/
Dopagem Esportivo
/
Anabolizantes
/
Cromatografia Gasosa-Espectrometria de Massas
/
Metandrostenolona
/
Métodos
/
Nandrolona
Limite:
Humanos
Idioma:
Chinês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2012
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS