Analysis of clinical features and early warning indicators of death from hand, foot and mouth disease in Shandong province / 中华预防医学杂志
Chinese Journal of Preventive Medicine
;
(12): 333-336, 2013.
Artigo
em Chinês
| WPRIM
| ID: wpr-274718
ABSTRACT
<p><b>OBJECTIVE</b>To understand the clinical features of death from hand, foot and mouth disease (HFMD) and to explore the early warning index of HFMD death.</p><p><b>METHODS</b>A total of 41 HFMD death cases were collected as case group in Shandong province between 2009 and 2011, and another 123 serious HFMD cases were selected as control group according to the similar gender, place of origin and hospital level, with the ratio at 13. We investigated the general situation, clinical treatment, past medical history, clinical symptoms and signs of the ill children, and applied the conditional logistic regression to explore early warning index of HFMD death.</p><p><b>RESULTS</b>The rate of patients who had symptoms in nervous system, digestive system, circulatory system and respiratory system were separately 90.2% (37/41), 58.5% (24/41), 53.7% (22/41) and 90.2% (37/41) in case group; and the proportions were 44.7% (55/123), 13.8% (17/123), 10.6% (13/123) and 12.2% (15/123) respectively in control group. The difference between the two groups showed statistical significance (χ(2) = 25.881, 32.791, 34.011, 86.505, P < 0.05). In case group, 37 patients had neurogenic pulmonary edema, 26 patients got encephalitis, 15 patients had respiratory and circulatory failure, 7 patients got pulmonary hemorrhage, 4 patients had multiple organ failure, 4 patients got myocarditis and 1 patient had cerebral hernia. According to multi-factor logistic regression analysis, the early warning indicators of HFMD death included neck resistance (case group 34.1% (14/41), control group 4.1% (5/123); OR = 7.145, 95%CI 1.748 - 29.204), vomiting (case group 58.5% (24/41), control group 13.8% (17/123); OR = 5.632, 95%CI 1.793 - 17.685) and increase of heart rate (case group 53.7% (22/41), control group 10.6% (14/123), OR = 6.370, 95%CI 1.517 - 26.743).</p><p><b>CONCLUSION</b>In the process of clinical treatment and care, we should interfere the serious HFMD patients with neck resistance, vomiting and increase of heart rate, and thereby reduce the death from HFMD.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Modelos Logísticos
/
China
/
Epidemiologia
/
Taxa de Sobrevida
/
Fatores de Risco
/
Mortalidade
/
Diagnóstico
/
Doença de Mão, Pé e Boca
Tipo de estudo:
Estudo diagnóstico
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Estudo de etiologia
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Estudo prognóstico
/
Fatores de risco
Limite:
Feminino
/
Humanos
/
Lactente
/
Masculino
/
Recém-Nascido
País/Região como assunto:
Ásia
Idioma:
Chinês
Revista:
Chinese Journal of Preventive Medicine
Ano de publicação:
2013
Tipo de documento:
Artigo
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