Effects of epimedium total flavonoids phytosomes on preventing and treating bone-loss of ovariectomized rats / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 221-224, 2002.
Artigo
em Chinês
| WPRIM
| ID: wpr-274977
ABSTRACT
<p><b>OBJECTIVE</b>To observe the effects of Epimedium total Flavonoids Phytosomes on preventing and treating bone-loss of the castrate osteoporosis rat model.</p><p><b>METHOD</b>The osteoporosis model was established with 4-month-odl panther's rats, their ovaries on both sides castrated. Dual energy X-ray scanning was used to determine the bone density, and immunity and ELASA were used to assay concentration of estradiol and IL-6 in serum respectively, then determine their effect.</p><p><b>RESULT</b>The BMP and E2 of high dosage group nilestriol group and normal group are higher than those of model group (P < 0.01), while their content of IL-6 is apparently lower than that of model group(P < 0.01).</p><p><b>CONCLUSION</b>The osteoporosis model was established successfully and the using of EFP can improve the bone density, enhance E2 level and decrease the IL-6 concentration in serum.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Osteoporose
/
Farmacologia
/
Fosfolipídeos
/
Flavonoides
/
Sangue
/
Portadores de Fármacos
/
Ovariectomia
/
Densidade Óssea
/
Química
/
Interleucina-6
Tipo de estudo:
Estudo prognóstico
Limite:
Animais
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2002
Tipo de documento:
Artigo
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