Triterpenoid saponins from bark Mitragyna inermis / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the constituents of Mitragyna inermis that have an anti-tumor activity on Bel-7402 of hepatic carcinoma.</p><p><b>METHOD</b>The compounds were isolated by column chromatography on silica gel, ODS, Sephadex LH-20 separately and their structures were elucidated by chemical and spectral technology.</p><p><b>RESULT</b>Three quinovic acid glycosides, quinovic acid 3 beta-beta-D-glucopyranosyl-(1-->4)-alpha-L-rhamnopyranosyl-28-O-beta- D-glucopyranoside(I), quinovic acid 3 beta-O-beta-D-quinovopyranoside(II), quinovic acid 3 beta-O-beta-D-glucopyranoside(III), were obtained.</p><p><b>CONCLUSION</b>I, II were isolated from Mitragyna for the first time.</p>