Heparin Anticoagulation and Natural Reversal in a Patient with Anaphylactoid Shock to Protamine: A case report / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 894-897, 2004.
Artigo
em Coreano
| WPRIM
| ID: wpr-27555
ABSTRACT
Protamine is the only agent approved to reverse heparin induced anticoagulation after cardiopulmonary bypass, although it may cause systemic hypotension, anaphylaxis or an anaphylactoid reaction, or pulmonary hypertension. However, there are no clinically available alternatives to protamine to neutralize systemic heparin in patients who are known to be allergic to protamine. We anesthetized a patient for mitral valve replacement who had previously an anaphylactoid shock to protamine. Because of the risk of an anaphylactoid shock, we allowed spontaneous reversal of heparin anticoagulation without the use of protamine after cardiopulmonary bypass and achieved a successful result. If a severe adverse reaction to protamine is suspected, it might be appropriate to allow the spontaneous reversal of heparin despite a greater risk of bleeding.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Choque
/
Heparina
/
Ponte Cardiopulmonar
/
Hemorragia
/
Hipertensão Pulmonar
/
Hipotensão
/
Anafilaxia
/
Valva Mitral
Limite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Anesthesiology
Ano de publicação:
2004
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS