Effect of toluene diisocyanate on lung function of workers / 中华劳动卫生职业病杂志
Chinese Journal of Industrial Hygiene and Occupational Diseases
;
(12): 844-845, 2013.
Artigo
em Chinês
| WPRIM
| ID: wpr-275801
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effect of long-term exposure to toluene diisocyanate (TDI) on the lung function of TDI-exposed workers.</p><p><b>METHODS</b>A factory was selected for this occupational epidemiological investigation. The workers who were exposed to TDI and had complete physical examination records in recent 3 years were the exposed group (n = 45), while the company's administrative staff, logistics staff, and other non-TDI-exposed workers who had complete physical examination records in recent 3 years were the control group (n = 47). The two groups were compared in terms of lung function indices.</p><p><b>RESULTS</b>Compared with the control group, the 2009 exposure group had significantly lower forced expiratory volume in one second (FEV1.0), FEV1.0/forced vital capacity (FVC), and maximal expiratory flow at 25% of FVC (MEF25) (P < 0.05), the 2010 exposure group had significantly lower FEV1.0, FEV1.0/FVC,maximum voluntary ventilation (MVV), and maximal expiratory flow at 50% of FVC (MEF50) (P < 0.05), and the 2011 exposure group had significantly lower FEV1.0, FEV1.0/FVC, peak expiratory flow (PEF), MEF25, and MEF50 (P < 0.05).</p><p><b>CONCLUSION</b>Long-term exposure to TDI can lead to certain impairment of lung function in workers, which may be reflected by decreased lung function indices such as vital capacity, FVC, FEV1.0, FEV1.0/FVC, PEF, and MVV.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Estudos de Casos e Controles
/
Capacidade Vital
/
Volume Expiratório Forçado
/
Exposição Ocupacional
/
Tolueno 2,4-Di-Isocianato
/
Pulmão
Tipo de estudo:
Estudo observacional
Limite:
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Industrial Hygiene and Occupational Diseases
Ano de publicação:
2013
Tipo de documento:
Artigo
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